In my senior portfolio class I was tasked to create a large editorial spread for an education article of my choice. I choose to design this article written by Tom Curtis who researched the actual origin of AIDS from square one.
I used left justified columns throughout the layout to make the large bodies of text easier to read. By doing this the readers eye is not distracted by the stepping of ragged text, considering the large amount of content displayed.
The graphics are used in a similar fashion to make the text as easy to read as possible while not distracting from the text but support the main idea in that corresponding paragraph or page.
The last page has a time-line that I instead displayed in graphics to tell the story, rather then words. Using the graphic time-line helps to break up the text and wrap the article up.